CRISPRepi

Details for DataSet_201

Sample info of the DataSet

Sample_accession	Sample_group	Organism	Target_gene	Data_type	sgRNA	sgRNA_Number_perVector	sgRNA_coordinate	PubMed	Data_source	Cell_type	Sample_Type	Notes
ERS2006762	case	Homo sapiens	OCT4,SOX2,KLF4,MYC,LIN28A,EEA-motif	RNA_seq	GGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CCCAGCACTTTGGG,AATCCCAGCACTTT,GCCTCCCAAAGTGC,GCTACTTGGGAGGC,GCCTCCCAAGTAGC,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG	25	chr9:107489778:-,chr3:181711719:+,chr9:107489882:-,chr3:181711828:+,chr9:107490086:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr9:107490137:-,chr3:130279534:+,chr8:127736037:+,chr5:177004089:-,chr8:127736014:+,chr5:172097293:+,chr8:127735970:+,chr3:178906840:+,chr6:31170765:+,chr8:127735889:+,chr17:50159097:-,chr6:31171306:-,chr8:127735841:+,chr9:107489727:-,chr6:31170866:-	29980666	E-MTAB-6186	CCD-1112Sk	cell line	p53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors; transfected with 36bp guide RNA
ERS2006763	case	Homo sapiens	OCT4,SOX2,KLF4,MYC,LIN28A,EEA-motif	RNA_seq	GGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CCCAGCACTTTGGG,AATCCCAGCACTTT,GCCTCCCAAAGTGC,GCTACTTGGGAGGC,GCCTCCCAAGTAGC,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG	25	chr9:107489778:-,chr3:181711719:+,chr9:107489882:-,chr3:181711828:+,chr9:107490086:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr9:107490137:-,chr3:130279534:+,chr8:127736037:+,chr5:177004089:-,chr8:127736014:+,chr5:172097293:+,chr8:127735970:+,chr3:178906840:+,chr6:31170765:+,chr8:127735889:+,chr17:50159097:-,chr6:31171306:-,chr8:127735841:+,chr9:107489727:-,chr6:31170866:-	29980666	E-MTAB-6186	CCD-1112Sk	cell line	p53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors; transfected with 36bp guide RNA
ERS2006764	case	Homo sapiens	OCT4,SOX2,KLF4,MYC,LIN28A,EEA-motif	RNA_seq	GGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CCCAGCACTTTGGG,AATCCCAGCACTTT,GCCTCCCAAAGTGC,GCTACTTGGGAGGC,GCCTCCCAAGTAGC,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG	25	chr9:107489778:-,chr3:181711719:+,chr9:107489882:-,chr3:181711828:+,chr9:107490086:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr9:107490137:-,chr3:130279534:+,chr8:127736037:+,chr5:177004089:-,chr8:127736014:+,chr5:172097293:+,chr8:127735970:+,chr3:178906840:+,chr6:31170765:+,chr8:127735889:+,chr17:50159097:-,chr6:31171306:-,chr8:127735841:+,chr9:107489727:-,chr6:31170866:-	29980666	E-MTAB-6186	CCD-1112Sk	cell line	p53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors; transfected with 36bp guide RNA
ERS2006765	case	Homo sapiens	OCT4,SOX2,KLF4,MYC,LIN28A,EEA-motif	RNA_seq	GGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CCCAGCACTTTGGG,AATCCCAGCACTTT,GCCTCCCAAAGTGC,GCTACTTGGGAGGC,GCCTCCCAAGTAGC,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG	25	chr9:107489778:-,chr3:181711719:+,chr9:107489882:-,chr3:181711828:+,chr9:107490086:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr9:107490137:-,chr3:130279534:+,chr8:127736037:+,chr5:177004089:-,chr8:127736014:+,chr5:172097293:+,chr8:127735970:+,chr3:178906840:+,chr6:31170765:+,chr8:127735889:+,chr17:50159097:-,chr6:31171306:-,chr8:127735841:+,chr9:107489727:-,chr6:31170866:-	29980666	E-MTAB-6186	CCD-1112Sk	cell line	p53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors; transfected with 36bp guide RNA
ERS2006750	control	Homo sapiens	NA	RNA_seq	NA	0	NA	29980666	E-MTAB-6186	CCD-1112Sk	cell line
ERS2006751	control	Homo sapiens	NA	RNA_seq	NA	0	NA	29980666	E-MTAB-6186	CCD-1112Sk	cell line
ERS2006752	control	Homo sapiens	NA	RNA_seq	NA	0	NA	29980666	E-MTAB-6186	CCD-1112Sk	cell line
ERS2006753	control	Homo sapiens	NA	RNA_seq	NA	0	NA	29980666	E-MTAB-6186	CCD-1112Sk	cell line

Gene expression profile

Scatter diagram of differential expression

Heatmap of unsupervised hierarchical clustering

Heatmap image

Function Enrichment Analysis of differentially expressed genes & Gene Set Enrichment Analysis (GSEA) of all expressed genes