Details for DataSet_204

Sample info of the DataSet

Sample_accession Sample_group Organism Target_gene Data_type sgRNA sgRNA_Number_perVector sgRNA_coordinate PubMed Data_source Cell_type Sample_Type Notes
ERS2006778caseHomo sapiensOCT4,SOX2,KLF4,MYC,LIN28ARNA_seqGGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG20chr8:127736014:+,chr3:181711719:+,chr8:127735970:+,chr3:181711828:+,chr8:127735889:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr8:127735841:+,chr9:107489727:-,chr9:107489778:-,chr9:107489882:-,chr9:107490086:+,chr6:31170765:+,chr9:107490137:-,chr6:31171306:-,chr8:127736037:+,chr6:31170866:-29980666E-MTAB-6186CCD-1112Skcell linep53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors
ERS2006779caseHomo sapiensOCT4,SOX2,KLF4,MYC,LIN28ARNA_seqGGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG20chr8:127736014:+,chr3:181711719:+,chr8:127735970:+,chr3:181711828:+,chr8:127735889:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr8:127735841:+,chr9:107489727:-,chr9:107489778:-,chr9:107489882:-,chr9:107490086:+,chr6:31170765:+,chr9:107490137:-,chr6:31171306:-,chr8:127736037:+,chr6:31170866:-29980666E-MTAB-6186CCD-1112Skcell linep53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors
ERS2006780caseHomo sapiensOCT4,SOX2,KLF4,MYC,LIN28ARNA_seqGGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG20chr8:127736014:+,chr3:181711719:+,chr8:127735970:+,chr3:181711828:+,chr8:127735889:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr8:127735841:+,chr9:107489727:-,chr9:107489778:-,chr9:107489882:-,chr9:107490086:+,chr6:31170765:+,chr9:107490137:-,chr6:31171306:-,chr8:127736037:+,chr6:31170866:-29980666E-MTAB-6186CCD-1112Skcell linep53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors
ERS2006781caseHomo sapiensOCT4,SOX2,KLF4,MYC,LIN28ARNA_seqGGGGGAGAAACTGAGGCGA,GGCACAGTGCCAGAGGTCTG,TCTGTGGGGGACCTGCACTG,GTGGCTGGCAGGCTGGCTCT,CAAAACCCGGCAGCGAGGCT,GCTGCCATAGCAACGATGGA,CCCTTTATAATGCGAGGGTC,GTGTCAGAGACCGGAGTTGT,CGGGGTACTCAAGTCTTCTA,TAATTATCTGCCCGGGGGGT,CGAACGTGTCTGCGGGCGCG,TATAAGTAAGGAACGCGCGC,GCTGCCATAGCAACGATGGA,GTTCGGTCGCTGCGCGACCA,TCTTCGCGGGCTTCGAACCC,CCCTTTATAATGCGAGGGTC,TCTCGCTAATCTCCGCCCAC,GGTTCCCAAAGCAGAGGGCG,AGCTAGAGTGCTCGGCTGCC,GCGCGCGTAGTTAATTCATG20chr8:127736014:+,chr3:181711719:+,chr8:127735970:+,chr3:181711828:+,chr8:127735889:+,chr9:107489882:-,chr8:127736037:+,chr1:26410614:+,chr1:26410514:+,chr1:26410351:+,chr8:127735841:+,chr9:107489727:-,chr9:107489778:-,chr9:107489882:-,chr9:107490086:+,chr6:31170765:+,chr9:107490137:-,chr6:31171306:-,chr8:127736037:+,chr6:31170866:-29980666E-MTAB-6186CCD-1112Skcell linep53 shRNA(+); 8 days after reprogramming; transfected with reprogramming factors
ERS2006750controlHomo sapiensNARNA_seqNA0NA29980666E-MTAB-6186CCD-1112Skcell line
ERS2006751controlHomo sapiensNARNA_seqNA0NA29980666E-MTAB-6186CCD-1112Skcell line
ERS2006752controlHomo sapiensNARNA_seqNA0NA29980666E-MTAB-6186CCD-1112Skcell line
ERS2006753controlHomo sapiensNARNA_seqNA0NA29980666E-MTAB-6186CCD-1112Skcell line

Gene expression profile

       

Scatter diagram of differential expression

Heatmap of unsupervised hierarchical clustering

Heatmap image


Function Enrichment Analysis of differentially expressed genes & Gene Set Enrichment Analysis (GSEA) of all expressed genes